Rejuran®
A medically-guided approach to improving skin quality, texture and resilience at the cellular level, without adding volume or altering facial shape.
East Melbourne, Richmond, Cremorne, Melbourne CBD, South Yarra, Albert ParkWhy patients choose this treatment
Patients often present with concerns such as:
“I look tired, even when I’m well-rested”
“My skin looks thinner or less resilient”
“I don’t want filler, but I want improvement”
“My skin quality has declined over time”
In many cases, these concerns are not related to volume loss alone, but to changes in skin quality itself.
What it is
A treatment focused on skin quality and structural support
Used to improve:
texture
hydration balance
overall skin resilience
What it is not
Not a volumising treatment
Not designed to change facial contours
Not an immediate-result procedure
Rejuran® is a medical skin treatment used in aesthetic practice to support overall skin quality.
It involves the use of polynucleotides (PN), biologically derived molecules that have been studied and utilised for their role in skin repair and regeneration.
How Rejuran® Works
Polynucleotides have been investigated for their interaction with:
Cellular repair pathways
Local inflammatory signalling
Fibroblast activity
In clinical practice, this is often discussed in the context of supporting skin quality over time, rather than producing immediate visible change.
At a cellular level, Rejuran acts primarily via signalling pathways that may promote fibroblast proliferation and up-regulates the synthesis of extracellular matrix components, including collagen and elastin. Rejuran may support cellular repair in metabolically stressed or damaged tissue.
This differs to energy devices such as lasers which cause a local trauma to the skin to achieve a response.
Over time, this may help improve skin texture, elasticity, and hydration. It may also improve the appearance of scars, pigmentation, texture and thinning skin.
Doctor-led assessment
At Cosmenon, treatment planning begins with a comprehensive medical consultation.
This includes:
Skin quality assessment
Structural vs surface analysis
Risk stratification
Determination of whether:
this treatment is appropriate
alternative treatments are more suitable
In some cases, no treatment may be recommended.
Where this fits in a treatment plan
This treatment is often used as:
A first step in improving skin quality
A complementary treatment alongside other procedures, such as skin needling.
A maintenance strategy over time
In many patients, improving skin quality first leads to more natural and predictable outcomes with any future treatments.
What to expect
Treatment performed after consultation and consent
Series-based approach often recommended
Gradual improvement over weeks to months
Individual response varies
Rejuran® is typically performed as a series-based treatment, depending on individual assessment.
Patients should understand:
There may be visible injection points and swelling initially
Short-term downtime is common
Changes, if they occur, tend to develop gradually
Safety and medical standards
Performed by a medical doctor
Use of regulated products sourced through Australian channels
Emergency protocols in place
Detailed aftercare and follow-up
Many aesthetic treatments are used in an off-label context. This is discussed during your consultation as part of informed consent.
Who this is suitable for?
Suitable:
Early to moderate skin quality concerns
Patients seeking subtle, natural improvement
Patients not wanting volumising treatments
Patients with heavy under-eye bags or with a history of
previous peri-opthalmic surgeries.
Not always suitable:
Significant structural volume loss
Severe skin laxity (may require alternative approaches)
Every treatment at Cosmenon begins with a medical consultation.
Frequently Asked Questions
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This is a key distinction.
Anti-wrinkle treatments act on muscle activity
Dermal fillers are primarily used to restore or create volume
Rejuran is used to improve skin quality without changing facial contours
For patients seeking subtle, natural improvement without volumisation, this may be an appropriate option following medical assessment.
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Common areas include:
Under-eye region
Cheeks
Peri-oral area
Neck
General facial skin
Suitability depends on individual anatomy and clinical assessment.
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Suitability varies.
This treatment may be considered for patients who:
Are concerned about skin quality, texture, or thinning skin
Prefer gradual, subtle changes
Do not wish to undergo volumising treatments
It may not be appropriate in cases where structural volume loss or significant skin laxity is the primary concern. In those situations, alternative approaches may be discussed.
A comprehensive consultation is required to determine the most appropriate plan.
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A series of treatments is often recommended rather than a single session.
The exact number and spacing depend on:
Skin condition
Treatment goals
Individual response
This is discussed in detail during your consultation.
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Changes are typically gradual.
Some patients may notice early improvements in skin hydration and texture within weeks, while more noticeable changes in skin quality may develop over a longer period.
Individual response varies, and outcomes cannot be guaranteed.
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Downtime is generally limited, but may include:
Redness
Swelling
Small injection-site marks
These are usually temporary and resolve over several days.
You will be provided with detailed aftercare instructions following treatment.
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Discomfort levels vary between individuals and treatment areas.
Measures are taken to improve comfort during the procedure, and this will be discussed with you prior to treatment.
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All medical procedures carry risk.
At Cosmenon:
Treatments are performed by a medical doctor
Products are sourced through regulated Australian suppliers
A comprehensive consultation and consent process is undertaken
Emergency protocols and medications are in place
Potential risks and side effects are discussed in detail prior to treatment.
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Yes, in many cases.
This treatment is often used:
As a first step in improving skin quality
Alongside other treatments as part of a broader plan
As a maintenance strategy over time
Treatment sequencing is important and is determined during consultation.
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A consultation ensures that:
Your concerns are properly assessed
The underlying cause is identified
The most appropriate treatment (or no treatment) is recommended
Risks, limitations, and alternatives are clearly explained
This is a critical part of safe, medically guided care.
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No.
Maintenance treatments may be required over time to sustain results, depending on individual factors and treatment goals.
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Many aesthetic treatments involve off-label use of products.
Where applicable, this is discussed as part of the informed consent process, in accordance with current Australian guidelines.